Medical Billing · Nationwide
Cytoreductive Surgery & Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Medical Billing Services
Multivisceral cytoreductive surgery (CRS) and 90-minute closed-circuit heated intraperitoneal chemoperfusion (HIPEC) for appendiceal adenocarcinoma, pseudomyxoma peritonei, colorectal peritoneal metastases, and ovarian carcinoma: peritonectomy, visceral resections, perfusion monitoring, and multi-specialty co-surgery.
Aethera Healthcare Solutions provides full-service medical billing and revenue cycle management to surgical oncologists, peritoneal surface malignancy surgeons, gynecologic oncologists, and advanced cancer centers across the United States. We handle coding, claims, payment posting, denial management, and A/R follow-up end to end — so your team can stay focused on patient care while your revenue cycle runs cleanly.
Typical cytoreductive surgery & hyperthermic intraperitoneal chemotherapy (hipec) CPT range we work: 49203, 49204, 49205, 49220, 96560, 77600, 44140, 44150, 44160, 38100, 47120, 49000, 99291.
Why cytoreductive surgery & hyperthermic intraperitoneal chemotherapy (hipec) billing leaks revenue
Chemotherapy perfusion administration (+96560) payer denial: Commercial payers and Medicare MACs rejecting heated peritoneal chemoperfusion add-on as experimental or bundled into exploratory laparotomy
Multivisceral peritonectomy (49203-49205) downcoding audits: Health plans downcoding extensive pelvic and diaphragmatic peritonectomies to simple omentectomy (49255)
Bowel resection and ostomy unbundling clawbacks: Payers bundling concomitant rectosigmoid resection (44140) or bowel anastomosis into cytoreduction codes
Dual-specialty surgical team Modifier -62 coordination: Rejection of co-surgery between surgical oncology and gynecologic oncology on combined pelvectomy and HIPEC
How Aethera fixes it
Specialty-trained coders (CPC/CCS) code to the documentation
First-pass claim scrubbing against payer and NCCI edits
Proactive denial prevention and 72-hour denial work
Relentless A/R follow-up to drive days-in-A/R down
Eligibility and prior-auth verification before service
Transparent, real-time reporting in the provider portal
Free tools for your billing team
Use these any time — no login required.
Cytoreductive Surgery & Hyperthermic Intraperitoneal Chemotherapy (HIPEC) billing FAQ
How should hyperthermic intraperitoneal chemotherapy (HIPEC) perfusion be coded?
HIPEC perfusion is commonly reported using CPT code 96560 (intraperitoneal chemotherapy administration, including preparation and monitoring) or unlisted chemotherapy administration (96549), often paired with CPT 77600/77605 (hyperthermia treatment) depending on payer-specific medical policies. Operative notes must detail chemotherapeutic agent (mitomycin-C or cisplatin), target temperature (41-43°C), 90-minute perfusion duration, and closed-circuit inflow/outflow catheter placement.
Are bowel resections separately reportable with cytoreductive peritonectomy?
Under CMS NCCI guidelines, bowel resections (such as segmental colectomy 44140 or low anterior resection 44145) performed for direct oncologic tumor clearance are separately billable with Modifier -51 or -59 from cytoreductive debulking of peritoneal implants (49203-49205), provided the operative dictation clearly describes distinct visceral mesenteric resection.